Publications

Journal Articles

F. Darbellay; C. Bochaton; L. Lopez-Delisle; B. Mascrez; P. Tschopp et al. : Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters. 2019-03-14. DOI : 10.1101/572875.
F. Darbellay; D. Duboule : Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters. 2019-03-14. DOI : 10.1101/572875.
B. K. Kragesteen; D. Duboule; S. Mundlos; M. Spielmann : Do RET somatic mutations play a role in Hirschsprung disease? Response. Genetics In Medicine. 2018-11-01. DOI : 10.1038/gim.2018.20.
N. Yakushiji-Kaminatsui; L. Lopez-Delisle; C. C. Bolt; G. Andrey; L. Beccari et al. : Similarities and differences in the regulation of HoxD genes during chick and mouse limb development. Plos Biology. 2018-11-01. DOI : 10.1371/journal.pbio.3000004.
L. Beccari; N. Moris; M. Girgin; D. A. Turner; P. Baillie-Johnson et al. : Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids. Nature. 2018-10-11. DOI : 10.1038/s41586-018-0578-0.
E. Rodriguez-Carballo; L. Lopez-Delisle; Y. Zhan; P. J. Fabre; L. Beccari et al. : The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes.. Genes & Development. 2017. DOI : 10.1101/gad.307769.117.
J. Zakany; F. Darbellay; B. Mascrez; A. Necsulea; D. Duboule : Control of growth and gut maturation by &ITHoxD&IT genes and the associated lncRNA &ITHaglr&IT. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2017. DOI : 10.1073/pnas.1712511114.
P. J. Fabre; M. Leleu; B. H. Mormann; L. Lopez-Delisle; D. Noordermeer et al. : Large scale genomic reorganization of topological domains at the HoxD locus. Genome Biology. 2017. DOI : 10.1186/s13059-017-1278-z.
A. R. Rodrigues; N. Yakushiji-Kaminatsui; Y. Atsuta; G. Andrey; P. Schorderet et al. : Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2017. DOI : 10.1073/pnas.1620767114.
A. R. Amandio; A. Necsulea; E. Joye; B. Mascrez; D. Duboule : Hotair Is Dispensible for Mouse Development. Plos Genetics. 2016. DOI : 10.1371/journal.pgen.1006232.
R. Schep; A. Necsulea; E. Rodriguez-Carballo; I. Guerreiro; G. Andrey et al. : Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2016. DOI : 10.1073/pnas.1617141113.
I. Guerreiro; S. Gitto; A. Novoa; J. Codourey; H. Thi Hanh Nguyen et al. : Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife. 2016. DOI : 10.7554/eLife.16087.
L. Beccari; N. Yakushiji-Kaminatsui; J. M. Woltering; A. Necsulea; N. Lonfat et al. : A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus. Genes & Development. 2016. DOI : 10.1101/gad.281055.116.
P. J. Fabre; A. Benke; E. Joye; T. H. Nguyen Huynh; S. Manley et al. : Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states. Proceedings of the National Academy of Sciences of the United States of America. 2015. DOI : 10.1073/pnas.1517972112.
J. M. Woltering; D. Duboule : Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model. Mechanisms Of Development. 2015. DOI : 10.1016/j.mod.2015.07.006.
N. Lonfat; D. Duboule : Structure, function and evolution of topologically associating domains (TADs) at HOX loci. FEBS letters. 2015. DOI : 10.1016/j.febslet.2015.04.024.
M. Vieux-Rochas; P. J. Fabre; M. Leleu; D. Duboule; D. Noordermeer : Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain. Proceedings of the National Academy of Sciences of the United States of America. 2015. DOI : 10.1073/pnas.1504783112.
A. R. Bassett; A. Akhtar; D. P. Barlow; A. P. Bird; N. Brockdorff et al. : Considerations when investigating IncRNA function in vivo. Elife. 2014. DOI : 10.7554/eLife.03058.
J. Lopez-Rios; A. Duchesne; D. Speziale; G. Andrey; K. A. Peterson et al. : Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs. NATURE. 2014. DOI : 10.1038/nature13289.
H. Jung; E. Mazzoni; N. Soshnikova; O. Hanley; B. Venkatesh et al. : Evolving Hox Activity Profiles Govern Diversity in Locomotor Systems. Developmental Cell. 2014. DOI : 10.1016/j.devcel.2014.03.008.
G. Andrey; D. Duboule : SnapShot: Hox Gene Regulation. Cell. 2014. DOI : 10.1016/j.cell.2014.01.060.
J. M. Woltering; D. Noordermeer; M. Leleu; D. Duboule : Conservation and Divergence of Regulatory Strategies at Hox Loci and the Origin of Tetrapod Digits. PLoS Biology. 2014. DOI : 10.1371/journal.pbio.1001773.
P. Schorderet; N. Lonfat; F. Darbellay; P. Tschopp; S. Gitto et al. : A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus. PLoS Genetics. 2013. DOI : 10.1371/journal.pgen.1003951.
W. De Laat; D. Duboule : Topology of mammalian developmental enhancers and their regulatory landscapes. Nature. 2013. DOI : 10.1038/nature12753.
S. Delpretti; T. Montavon; M. Leleu; E. Joye; A. Tzika et al. : Multiple Enhancers Regulate Hoxd Genes and the Hotdog LncRNA during Cecum Budding. Cell reports. 2013. DOI : 10.1016/j.celrep.2013.09.002.
I. Guerreiro; A. Nunes; J. M. Woltering; A. Casaca; A. Novoa et al. : Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2013. DOI : 10.1073/pnas.1300592110.
M. Vieux-Rochas; B. Mascrez; R. Krumlauf; D. Duboule : Combined function of HoxA and HoxB clusters in neural crest cells. Developmental biology. 2013. DOI : 10.1016/j.ydbio.2013.06.027.
G. Andrey; T. Montavon; B. Mascrez; F. Gonzalez; D. Noordermeer et al. : A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science (New York, N.Y.). 2013. DOI : 10.1126/science.1234167.
D. Noordermeer; D. Duboule : Chromatin architectures and hox gene collinearity. Current topics in developmental biology. 2013. DOI : 10.1016/B978-0-12-416027-9.00004-8.
N. Soshnikova; R. Dewaele; P. Janvier; R. Krumlauf; D. Duboule : Duplications of hox gene clusters and the emergence of vertebrates. Developmental biology. 2013. DOI : 10.1016/j.ydbio.2013.03.004.
J. Zakany; D. Duboule : A Genetic Basis for Altered Sexual Behavior in Mutant Female Mice. Current Biology. 2012. DOI : 10.1016/j.cub.2012.06.067.
T. Montavon; D. Duboule : Landscapes and archipelagos: spatial organization of gene regulation in vertebrates. Trends in Cell Biology. 2012. DOI : 10.1016/j.tcb.2012.04.003.
S. Delpretti; J. Zakany; D. Duboule : A function for all posterior Hoxd genes during digit development?. Developmental dynamics : an official publication of the American Association of Anatomists. 2012. DOI : 10.1002/dvdy.23756.
P. Tschopp; A. J. Christen; D. Duboule : Bimodal control of Hoxd gene transcription in the spinal cord defines two regulatory subclusters. Development. 2012. DOI : 10.1242/dev.076794.
T. Montavon; N. Soshnikova; B. Mascrez; E. Joye; L. Thevenet et al. : A regulatory archipelago controls hox genes transcription in digits. Cell. 2011. DOI : 10.1016/j.cell.2011.10.023.
P. Tschopp; D. Duboule : A genetic approach to the transcriptional regulation of hox gene clusters. Annual review of genetics. 2011. DOI : 10.1146/annurev-genet-102209-163429.
D. Noordermeer; M. Leleu; E. Splinter; J. Rougemont; W. De Laat et al. : The dynamic architecture of Hox gene clusters. Science (New York, N.Y.). 2011. DOI : 10.1126/science.1207194.
I. Gyurján; B. Sonderegger; F. Naef; D. Duboule : Analysis of the dynamics of limb transcriptomes during mouse development. BMC developmental biology. 2011. DOI : 10.1186/1471-213X-11-47.
P. Schorderet; D. Duboule : Structural and functional differences in the long non-coding RNA hotair in mouse and human. PLoS genetics. 2011. DOI : 10.1371/journal.pgen.1002071.
P. Tschopp; N. Fraudeau; F. Béna; D. Duboule : Reshuffling genomic landscapes to study the regulatory evolution of Hox gene clusters. Proceedings of the National Academy of Sciences of the United States of America. 2011. DOI : 10.1073/pnas.1102985108.
P. Tschopp; D. Duboule : A regulatory ‘landscape effect’ over the Hoxd cluster. Developmental Biology. 2011. DOI : 10.1016/j.ydbio.2010.12.034.
M. Friedli; I. Barde; M. Arcangeli; S. Verp; A. Quazzola et al. : A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the olig1 and olig2 locus. PloS one. 2010. DOI : 10.1371/journal.pone.0015741.
N. Soshnikova; T. Montavon; M. Leleu; N. Galjart; D. Duboule : Functional analysis of CTCF during mammalian limb development. Developmental cell. 2010. DOI : 10.1016/j.devcel.2010.11.009.
N. Di-Poï; J. I. Montoya-Burgos; H. Miller; O. Pourquié; M. C. Milinkovitch et al. : Changes in Hox genes' structure and function during the evolution of the squamate body plan. Nature. 2010. DOI : 10.1038/nature08789.
N. Di-Poï; U. Koch; F. Radtke; D. Duboule : Additive and global functions of HoxA cluster genes in mesoderm derivatives. Developmental biology. 2010. DOI : 10.1016/j.ydbio.2010.03.006.
J. M. Woltering; D. Duboule : The origin of digits: expression patterns versus regulatory mechanisms. Developmental cell. 2010. DOI : 10.1016/j.devcel.2010.04.002.
P. Villavicencio-Lorini; P. Kuss; J. Friedrich; J. Haupt; M. Farooq et al. : Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. The Journal of clinical investigation. 2010. DOI : 10.1172/JCI41554.
D. Duboule : The evo-devo comet. Embo Reports. 2010. DOI : 10.1038/embor.2010.94.
N. Soshnikova; D. Duboule : Epigenetic temporal control of mouse Hox genes in vivo. Science. 2009. DOI : 10.1126/science.1171468.
M-O. Sauvain; A. P. Dorr; B. Stevenson; A. Quazzola; F. Naef et al. : Genotypic features of lentivirus transgenic mice. Journal of virology. 2008. DOI : 10.1128/JVI.00623-08.
J. Auwerx; P. Avner; R. Baldock; A. Ballabio; R. Balling et al. : The European dimension for the mouse genome mutagenesis program. Nature genetics. 2004. DOI : 10.1038/ng0904-925.

Conference Papers

F. Darbellay; J. Zakany; B. Mascrez; D. Duboule : Hox Genes Regulation During Vertebrate Development and Evolution. 2017. 18th International Congress of Developmental Biology, Natil Univ Singapore, Singapore, SINGAPORE, JUN 18-22, 2017. p. S13-S14. DOI : 10.1016/j.mod.2017.04.562.
S. Manley; K. Douglass; V. Pfeiffer; A. Vancevska; P. Fabre et al. : Nanoscale Spatial Organization of Chromatin in its Cellular Context, from Telomeres to Hox. 2016. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, FEB 27-MAR 02, 2016. p. 485A-485A.
D. Duboule : A genetic approach of long-range gene regulation during development and evolution. 2016. p. 219-220.
S. Verp; M. Blom; M. Friedli; S. Delpretti; I. Barde et al. : Lentiviral vectors mediated transgenesis. 2011. p. 1170-1170.

Reviews

J. Deschamps; D. Duboule : Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock. 2017.
P. J. Fabre; A. Benke; S. Manley; D. Duboule : Visualizing the HoxD Gene Cluster at the Nanoscale Level. 2015.
D. Noordermeer; D. Duboule : Chromatin looping and organization at developmentally regulated gene loci. 2013.
D. Duboule : The rise and fall of Hox gene clusters. 2007.

Theses

F. Darbellay / D. Duboule (Dir.) Coordinated Hoxd genes expression during embryogenesis is dependent on a strict disposition of genes and polarized regulators within the HoxD cluster. Lausanne: EPFL, 2018. DOI : 10.5075/epfl-thesis-8604.
N. Lonfat / D. Duboule (Dir.) An ancestral regulatory mechanism underlies Hoxd gene expression in both developing genitals and digits. Lausanne: EPFL, 2013. DOI : 10.5075/epfl-thesis-5997.
G. Andrey / D. Duboule (Dir.) Regulatory Switches Underlie Hoxd Gene Activation in Tetrapod Limbs. Lausanne: EPFL, 2013. DOI : 10.5075/epfl-thesis-5716.
P. Schorderet / D. Duboule (Dir.) Polycomb Recruitment and Targeting in Mammals. Lausanne: EPFL, 2013. DOI : 10.5075/epfl-thesis-5679.
S. Delpretti Anex / D. Duboule (Dir.) Mechanisms of Hoxd gene regulation during the development and evolution of the intestinal caecum. Lausanne: EPFL, 2013. DOI : 10.5075/epfl-thesis-5597.

Book Chapters

F. Darbellay; D. Duboule : Topological Domains, Metagenes, and the Emergence of Pleiotropic Regulations at Hox Loci ; Essays On Developmental Biology, Pt A; San Diego: Elsevier Academic Press Inc, 2016. p. 299-314.
F. Spitz; D. Duboule : Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution ; Long-Range Control of Gene Expression; Elsevier Inc, 2008. p. 175-205.

Student Projects

P. Schorderet : Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency. 2008.
S. Delpretti; T. Montavon : Hoxd gene regulation in the developing caecum. 2008.

2019

F. Darbellay; C. Bochaton; L. Lopez-Delisle; B. Mascrez; P. Tschopp et al. : Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters. 2019-03-14. DOI : 10.1101/572875.
F. Darbellay; D. Duboule : Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters. 2019-03-14. DOI : 10.1101/572875.

2018

P. J. Fabre; M. Leleu; B. Mascrez; Q. Lo Giudice; J. Cobb et al. : Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development; Bmc Biology. 2018-09-18. DOI : 10.1186/s12915-018-0570-z.
I. Janoueix-Lerosey; L. Lopez-Delisle; O. Delattre; H. Rohrer : The ALK receptor in sympathetic neuron development and neuroblastoma; CELL AND TISSUE RESEARCH. 2018. DOI : 10.1007/s00441-017-2784-8.
R. Flottmann; B. Kragesteen; S. Geuer; M. Socha; L. Allou et al. : Noncoding copy-number variations are associated with congenital limb malformation; GENETICS IN MEDICINE. 2018. DOI : 10.1038/gim.2017.154.
F. Darbellay / D. Duboule (Dir.) : Coordinated Hoxd genes expression during embryogenesis is dependent on a strict disposition of genes and polarized regulators within the HoxD cluster. Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8604.

2017

E. Rodriguez-Carballo; L. Lopez-Delisle; Y. Zhan; P. J. Fabre; L. Beccari et al. : The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes.; Genes & Development. 2017. DOI : 10.1101/gad.307769.117.
J. Zakany; F. Darbellay; B. Mascrez; A. Necsulea; D. Duboule : Control of growth and gut maturation by &ITHoxD&IT genes and the associated lncRNA &ITHaglr⁢ Proceedings Of The National Academy Of Sciences Of The United States Of America. 2017. DOI : 10.1073/pnas.1712511114.
J. Deschamps; D. Duboule : Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock; Genes & Development. 2017. DOI : 10.1101/gad.303123.117.
P. J. Fabre; M. Leleu; B. H. Mormann; L. Lopez-Delisle; D. Noordermeer et al. : Large scale genomic reorganization of topological domains at the HoxD locus; Genome Biology. 2017. DOI : 10.1186/s13059-017-1278-z.
F. Darbellay; J. Zakany; B. Mascrez; D. Duboule : Hox Genes Regulation During Vertebrate Development and Evolution. 2017. 18th International Congress of Developmental Biology, Natil Univ Singapore, Singapore, SINGAPORE, JUN 18-22, 2017. p. S13-S14. DOI : 10.1016/j.mod.2017.04.562.
A. R. Rodrigues; N. Yakushiji-Kaminatsui; Y. Atsuta; G. Andrey; P. Schorderet et al. : Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2017. DOI : 10.1073/pnas.1620767114.

2016

A. R. Amandio; A. Necsulea; E. Joye; B. Mascrez; D. Duboule : Hotair Is Dispensible for Mouse Development; Plos Genetics. 2016. DOI : 10.1371/journal.pgen.1006232.
R. Schep; A. Necsulea; E. Rodriguez-Carballo; I. Guerreiro; G. Andrey et al. : Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2016. DOI : 10.1073/pnas.1617141113.
I. Guerreiro; S. Gitto; A. Novoa; J. Codourey; H. Thi Hanh Nguyen et al. : Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan; Elife. 2016. DOI : 10.7554/eLife.16087.
F. Darbellay; D. Duboule : Topological Domains, Metagenes, and the Emergence of Pleiotropic Regulations at Hox Loci; Essays On Developmental Biology, Pt A; San Diego: Elsevier Academic Press Inc, 2016. p. 299-314.
S. Manley; K. Douglass; V. Pfeiffer; A. Vancevska; P. Fabre et al. : Nanoscale Spatial Organization of Chromatin in its Cellular Context, from Telomeres to Hox. 2016. 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, FEB 27-MAR 02, 2016. p. 485A-485A.
L. Beccari; N. Yakushiji-Kaminatsui; J. M. Woltering; A. Necsulea; N. Lonfat et al. : A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus; Genes & Development. 2016. DOI : 10.1101/gad.281055.116.
D. Duboule : A genetic approach of long-range gene regulation during development and evolution. 2016. p. 219-220.

2015

O. Joshi; S.-Y. Wang; T. Kuznetsova; Y. Atlasi; T. Peng et al. : Dynamic Reorganization of Extremely Long-Range Promoter-Promoter Interactions between Two States of Pluripotency; Cell Stem Cell. 2015. DOI : 10.1016/j.stem.2015.11.010.
P. J. Fabre; A. Benke; S. Manley; D. Duboule : Visualizing the HoxD Gene Cluster at the Nanoscale Level; Cold Spring Harbor symposia on quantitative biology. 2015. DOI : 10.1101/sqb.2015.80.027177.
P. J. Fabre; A. Benke; E. Joye; T. H. Nguyen Huynh; S. Manley et al. : Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states; Proceedings of the National Academy of Sciences of the United States of America. 2015. DOI : 10.1073/pnas.1517972112.
J. M. Woltering; D. Duboule : Tetrapod axial evolution and developmental constraints; Empirical underpinning by a mouse model; Mechanisms Of Development. 2015. DOI : 10.1016/j.mod.2015.07.006.
N. Lonfat; D. Duboule : Structure, function and evolution of topologically associating domains (TADs) at HOX loci; FEBS letters. 2015. DOI : 10.1016/j.febslet.2015.04.024.
R. A. W. Wiberg; D. L. Halligan; R. W. Ness; A. Necsulea; H. Kaessmann et al. : Assessing Recent Selection and Functionality at Long Noncoding RNA Loci in the Mouse Genome; Genome Biology And Evolution. 2015. DOI : 10.1093/gbe/evv155.
M. Vieux-Rochas; P. J. Fabre; M. Leleu; D. Duboule; D. Noordermeer : Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain; Proceedings of the National Academy of Sciences of the United States of America. 2015. DOI : 10.1073/pnas.1504783112.

2014

A. Necsulea; H. Kaessmann : Evolutionary dynamics of coding and non-coding transcriptomes; Nature Reviews Genetics. 2014. DOI : 10.1038/nrg3802.
N. Lonfat; T. Montavon; F. Darbellay; S. Gitto; D. Duboule : Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci; Science. 2014. DOI : 10.1126/science.1257493.
A. R. Bassett; A. Akhtar; D. P. Barlow; A. P. Bird; N. Brockdorff et al. : Considerations when investigating IncRNA function in vivo; Elife. 2014. DOI : 10.7554/eLife.03058.
J. Lopez-Rios; A. Duchesne; D. Speziale; G. Andrey; K. A. Peterson et al. : Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs; NATURE. 2014. DOI : 10.1038/nature13289.
D. Noordermeer; M. Leleu; P. Schorderet; E. Joye; F. Chabaud et al. : Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci; eLife. 2014. DOI : 10.7554/eLife.02557.
H. Jung; E. Mazzoni; N. Soshnikova; O. Hanley; B. Venkatesh et al. : Evolving Hox Activity Profiles Govern Diversity in Locomotor Systems; Developmental Cell. 2014. DOI : 10.1016/j.devcel.2014.03.008.
G. Andrey; D. Duboule : SnapShot: Hox Gene Regulation; Cell. 2014. DOI : 10.1016/j.cell.2014.01.060.
A. Necsulea; M. Soumillon; M. Warnefors; A. Liechti; T. Daish et al. : The evolution of lncRNA repertoires and expression patterns in tetrapods; Nature. 2014. DOI : 10.1038/nature12943.
F. P. A. David; J. Delafontaine; S. Carat; F. J. Ross; G. Lefebvre et al. : HTSstation: A Web Application and Open-Access Libraries for High-Throughput Sequencing Data Analysis; PLoS ONE. 2014. DOI : 10.1371/journal.pone.0085879.
J. M. Woltering; D. Noordermeer; M. Leleu; D. Duboule : Conservation and Divergence of Regulatory Strategies at Hox Loci and the Origin of Tetrapod Digits; PLoS Biology. 2014. DOI : 10.1371/journal.pbio.1001773.

2013

N. Gheldof; R. M. Witwicki; E. Migliavacca; M. Leleu; G. Didelot et al. : Structural Variation-Associated Expression Changes Are Paralleled by Chromatin Architecture Modifications; Plos One. 2013. DOI : 10.1371/journal.pone.0079973.
F. J. Vonk; N. R. Casewell; C. V. Henkel; A. M. Heimberg; H. J. Jansen et al. : The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system; Proceedings of the National Academy of Sciences. 2013. DOI : 10.1073/pnas.1314702110.
N. Lonfat / D. Duboule (Dir.) : An ancestral regulatory mechanism underlies Hoxd gene expression in both developing genitals and digits. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5997.
P. Schorderet; N. Lonfat; F. Darbellay; P. Tschopp; S. Gitto et al. : A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus; PLoS Genetics. 2013. DOI : 10.1371/journal.pgen.1003951.
W. De Laat; D. Duboule : Topology of mammalian developmental enhancers and their regulatory landscapes; Nature. 2013. DOI : 10.1038/nature12753.
S. Delpretti; T. Montavon; M. Leleu; E. Joye; A. Tzika et al. : Multiple Enhancers Regulate Hoxd Genes and the Hotdog LncRNA during Cecum Budding; Cell reports. 2013. DOI : 10.1016/j.celrep.2013.09.002.
I. Guerreiro; A. Nunes; J. M. Woltering; A. Casaca; A. Novoa et al. : Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine; Proceedings Of The National Academy Of Sciences Of The United States Of America. 2013. DOI : 10.1073/pnas.1300592110.
M. Vieux-Rochas; B. Mascrez; R. Krumlauf; D. Duboule : Combined function of HoxA and HoxB clusters in neural crest cells; Developmental biology. 2013. DOI : 10.1016/j.ydbio.2013.06.027.
N. Lonfat; T. Montavon; D. Jebb; P. Tschopp; T. H. Nguyen Huynh et al. : Transgene- and locus-dependent imprinting reveals allele-specific chromosome conformations; Proceedings of the National Academy of Sciences. 2013. DOI : 10.1073/pnas.1310704110.
G. Andrey; T. Montavon; B. Mascrez; F. Gonzalez; D. Noordermeer et al. : A switch between topological domains underlies HoxD genes collinearity in mouse limbs; Science (New York, N.Y.). 2013. DOI : 10.1126/science.1234167.
T. Montavon; D. Duboule : Chromatin organization and global regulation of Hox gene clusters; Philosophical Transactions of the Royal Society B: Biological Sciences. 2013. DOI : 10.1098/rstb.2012.0367.
D. Noordermeer; D. Duboule : Chromatin architectures and hox gene collinearity; Current topics in developmental biology. 2013. DOI : 10.1016/B978-0-12-416027-9.00004-8.
N. Soshnikova; R. Dewaele; P. Janvier; R. Krumlauf; D. Duboule : Duplications of hox gene clusters and the emergence of vertebrates; Developmental biology. 2013. DOI : 10.1016/j.ydbio.2013.03.004.
G. Andrey / D. Duboule (Dir.) : Regulatory Switches Underlie Hoxd Gene Activation in Tetrapod Limbs. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5716.
P. Schorderet / D. Duboule (Dir.) : Polycomb Recruitment and Targeting in Mammals. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5679.
D. Noordermeer; D. Duboule : Chromatin looping and organization at developmentally regulated gene loci; Wiley Interdisciplinary Reviews: Developmental Biology. 2013. DOI : 10.1002/wdev.103.
S. Delpretti Anex / D. Duboule (Dir.) : Mechanisms of Hoxd gene regulation during the development and evolution of the intestinal caecum. Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5597.

2012

T. Montavon; L. Thevenet; D. Duboule : Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus; Proceedings of the National Academy of Sciences. 2012. DOI : 10.1073/pnas.1217659109.
J. Zakany; D. Duboule : A Genetic Basis for Altered Sexual Behavior in Mutant Female Mice; Current Biology. 2012. DOI : 10.1016/j.cub.2012.06.067.
T. Montavon; D. Duboule : Landscapes and archipelagos: spatial organization of gene regulation in vertebrates; Trends in Cell Biology. 2012. DOI : 10.1016/j.tcb.2012.04.003.
S. Delpretti; J. Zakany; D. Duboule : A function for all posterior Hoxd genes during digit development?; Developmental dynamics : an official publication of the American Association of Anatomists. 2012. DOI : 10.1002/dvdy.23756.
P. Tschopp; A. J. Christen; D. Duboule : Bimodal control of Hoxd gene transcription in the spinal cord defines two regulatory subclusters; Development. 2012. DOI : 10.1242/dev.076794.

2011

N. Gheldof; M. Leleu; D. Noordermeer; J. Rougemont; A. Reymond : Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method; Methods in molecular biology (Clifton, N.J.); Springer Science+Business Media, 2011. p. 211-25.
S. Verp; M. Blom; M. Friedli; S. Delpretti; I. Barde et al. : Lentiviral vectors mediated transgenesis. 2011. p. 1170-1170.
T. Montavon; N. Soshnikova; B. Mascrez; E. Joye; L. Thevenet et al. : A regulatory archipelago controls hox genes transcription in digits; Cell. 2011. DOI : 10.1016/j.cell.2011.10.023.
P. Tschopp; D. Duboule : A genetic approach to the transcriptional regulation of hox gene clusters; Annual review of genetics. 2011. DOI : 10.1146/annurev-genet-102209-163429.
D. Noordermeer; M. Leleu; E. Splinter; J. Rougemont; W. De Laat et al. : The dynamic architecture of Hox gene clusters; Science (New York, N.Y.). 2011. DOI : 10.1126/science.1207194.
I. Gyurján; B. Sonderegger; F. Naef; D. Duboule : Analysis of the dynamics of limb transcriptomes during mouse development; BMC developmental biology. 2011. DOI : 10.1186/1471-213X-11-47.
P. Schorderet; D. Duboule : Structural and functional differences in the long non-coding RNA hotair in mouse and human; PLoS genetics. 2011. DOI : 10.1371/journal.pgen.1002071.
P. Tschopp; N. Fraudeau; F. Béna; D. Duboule : Reshuffling genomic landscapes to study the regulatory evolution of Hox gene clusters; Proceedings of the National Academy of Sciences of the United States of America. 2011. DOI : 10.1073/pnas.1102985108.
P. Tschopp; D. Duboule : A regulatory ‘landscape effect’ over the Hoxd cluster; Developmental Biology. 2011. DOI : 10.1016/j.ydbio.2010.12.034.

2010

M. Friedli; I. Barde; M. Arcangeli; S. Verp; A. Quazzola et al. : A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the olig1 and olig2 locus; PloS one. 2010. DOI : 10.1371/journal.pone.0015741.
N. Soshnikova; T. Montavon; M. Leleu; N. Galjart; D. Duboule : Functional analysis of CTCF during mammalian limb development; Developmental cell. 2010. DOI : 10.1016/j.devcel.2010.11.009.
N. Di-Poï; J. I. Montoya-Burgos; H. Miller; O. Pourquié; M. C. Milinkovitch et al. : Changes in Hox genes' structure and function during the evolution of the squamate body plan; Nature. 2010. DOI : 10.1038/nature08789.
N. Di-Poï; U. Koch; F. Radtke; D. Duboule : Additive and global functions of HoxA cluster genes in mesoderm derivatives; Developmental biology. 2010. DOI : 10.1016/j.ydbio.2010.03.006.
J. M. Woltering; D. Duboule : The origin of digits: expression patterns versus regulatory mechanisms; Developmental cell. 2010. DOI : 10.1016/j.devcel.2010.04.002.
P. Villavicencio-Lorini; P. Kuss; J. Friedrich; J. Haupt; M. Farooq et al. : Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation; The Journal of clinical investigation. 2010. DOI : 10.1172/JCI41554.
D. Duboule : The evo-devo comet; Embo Reports. 2010. DOI : 10.1038/embor.2010.94.

2009

N. Soshnikova; D. Duboule : Epigenetic regulation of vertebrate Hox genes: a dynamic equilibrium; Epigenetics. 2009. DOI : 10.4161/epi.4.8.10132.
D. Duboule : The Hox complex - an interview with Denis Duboule. Interviewed by Richardson, Michael K; Int J Dev Biol. 2009. DOI : 10.1387/ijdb.072558mr.
N. Soshnikova; D. Duboule : Epigenetic control of hox genes collinear activation during vertebrate development. 2009. 16th Annual Conference of the International-Society-of-Development-Biologists, Edinburg, Scotland, September 6-10 2009. p. S6-S7. DOI : 10.1016/j.mod.2009.06.956.
A. E. Fortunato; T. Kondoh; D. Duboule; N. Holder; S. Wilson et al. : Somitogenesis and development of primary motor neurons: The role of the homeobox uncx4.1. 2009. 16th Annual Conference of the International-Society-of-Development-Biologists, Edinburg, Scotland, September 6-10 2009. p. S180-S181. DOI : 10.1016/j.mod.2009.06.432.
N. Di-Poi; J. I. Montoya-Burgos; H. Miller; N. Denans; O. Pourquie et al. : A typical relaxation of structural constraints in Hox gene clusters of squamates. 2009. 16th Annual Conference of the International-Society-of-Development-Biologists, Edinburg, Scotland, September 06-10 2009. p. S250. DOI : 10.1016/j.mod.2009.06.655.
T. Montavon; B. Mascrez; F. Spitz; W. de Laat; D. Duboule : Long-range enhancer-promoter interactions in the HoxD complex. 2009. 16th Annual Conference of the International-Society-of-Development-Biologists, Edinburg, Scotland, September 06-10 2009. p. S335. DOI : 10.1016/j.mod.2009.06.1232.
N. Soshnikova; D. Duboule : Epigenetic temporal control of mouse Hox genes in vivo; Science. 2009. DOI : 10.1126/science.1171468.
P. Tschopp; B. Tarchini; F. Spitz; J. Zakany; D. Duboule : Uncoupling time and space in the collinear regulation of Hox genes; PLoS Genet. 2009. DOI : 10.1371/journal.pgen.1000398.
J. M. Woltering; D. Duboule : Conserved elements within open reading frames of mammalian Hox genes; Journal of Biology. 2009. DOI : 10.1186/jbiol116.
N. Di-Poi; J. I. Montoya-Burgos; D. Duboule : Atypical relaxation of structural constraints in Hox gene clusters of the green anole lizard; Genome Research. 2009. DOI : 10.1101/gr.087932.108.
M. Minoux; G. S. Antonarakis; M. Kmita; D. Duboule; F. M. Rijli : Rostral and caudal pharyngeal arches share a common neural crest ground pattern; Development. 2009. DOI : 10.1242/dev.028621.

2008

N. Soshnikova; D. Duboule : Epigenetic regulation of Hox gene activation: the waltz of methyls; Bioessays. 2008. DOI : 10.1002/bies.20724.
C. Morey; N. R. Da Silva; M. Kmita; D. Duboule; W. A. Bickmore : Ectopic nuclear reorganisation driven by a Hoxb1 transgene transposed into Hoxd; journal of lipid research. 2008. DOI : 10.1242/jcs.023234.
M. Friedli; S. Nikolaev; R. Lyle; M. Arcangeli; D. Duboule et al. : Characterization of mouse Dactylaplasia mutations: a model for human ectrodactyly SHFM3; Mamm Genome. 2008. DOI : 10.1007/s00335-008-9106-0.
F. Spitz; D. Duboule : Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution; Long-Range Control of Gene Expression; Elsevier Inc, 2008. p. 175-205.
M.-O. Sauvain; A. P. Dorr; B. Stevenson; A. Quazzola; F. Naef et al. : Genotypic features of lentivirus transgenic mice; Journal of virology. 2008. DOI : 10.1128/JVI.00623-08.
T. Montavon; J. F. Le Garrec; M. Kerszberg; D. Duboule : Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness; Genes Dev. 2008. DOI : 10.1101/gad.1631708.

2007

D. Duboule : The rise and fall of Hox gene clusters; Development. 2007.
D. Duboule; B. Tarchini; J. Zakany; M. Kmita : Tinkering with constraints in the evolution of the vertebrate limb anterior-posterior polarity. 2007. Novartis Foundation Symposium. p. 130-7; discussion 138-41, 158-63.
J. Zakany; D. Duboule : The role of Hox genes during vertebrate limb development; Curr Opin Genet Dev. 2007.
J. Zakany; G. Zacchetti; D. Duboule : Interactions between HOXD and Gli3 genes control the limb apical ectodermal ridge via Fgf10; Dev Biol. 2007. DOI : 10.1016/j.ydbio.2007.03.517.
G. Zacchetti; D. Duboule; J. Zakany : Hox gene function in vertebrate gut morphogenesis: the case of the caecum; Development. 2007. DOI : 10.1242/dev.010991.
F. G. Grosveld; D. Duboule : Differentiation and gene regulation; Curr Opin Genet Dev. 2007. DOI : 10.1016/j.gde.2007.10.001.
F. Gonzalez; D. Duboule; F. Spitz : Transgenic analysis of Hoxd gene regulation during digit development; Dev Biol. 2007. DOI : 10.1016/j.ydbio.2007.03.020.
N. Di-Poi; J. Zakany; D. Duboule : Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development; PLoS Genet. 2007. DOI : 10.1371/journal.pgen.0030232.

2006

C. D. Stern; J. Charite; J. Deschamps; D. Duboule; A. J. Durston et al. : Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems?; Int J Dev Biol. 2006.
B. Tarchini; D. Duboule; M. Kmita : Regulatory constraints in the evolution of the tetrapod limb anterior-posterior polarity; Nature. 2006. DOI : 10.1038/nature05247.
B. Tarchini; D. Duboule : Control of Hoxd genes' collinearity during early limb development; Dev Cell. 2006. DOI : 10.1016/j.devcel.2005.11.014.
F. Spitz; C. Herkenne; C. Hinard; D. Duboule : A STRING lifts the veil on the mechanisms controlling Hox genes expression; Med Sci (Paris). 2006.
J. Cobb; A. Dierich; Y. Huss-Garcia; D. Duboule : A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development; Proc Natl Acad Sci U.S.A. 2006. DOI : 10.1073/pnas.0510544103.

2005

D. Duboule : Evolution and Development: a long and winding road; Science. 2005.
B. Tarchini; T. H. Huynh; G. A. Cox; D. Duboule : HoxD cluster scanning deletions identify multiple defects leading to paralysis in the mouse mutant Ironside; Genes Dev. 2005. DOI : 10.1101/gad.351105.
F. Spitz; C. Herkenne; M. A. Morris; D. Duboule : Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes; Nat Genet. 2005. DOI : 10.1038/ng1597.
F. Spitz; D. Duboule : Developmental biology: reproduction in clusters; Nature. 2005. DOI : 10.1038/434715a.
M. Kmita; B. Tarchini; J. Zakany; M. Logan; C. J. Tabin et al. : Early developmental arrest of mammalian limbs lacking HoxA/HoxD gene function; Nature. 2005. DOI : 10.1038/nature03648.
J. Cobb; D. Duboule : Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia; Development. 2005. DOI : 10.1242/dev.01885.
S. Brown; P. Chambon; M. H. De Angelis : EMPReSS: standardized phenotype screens for functional annotation of the mouse genome; Nature Genetics. 2005. DOI : 10.1038/ng1105-1155.

2004

J. Auwerx; P. Avner; R. Baldock; A. Ballabio; R. Balling et al. : The European dimension for the mouse genome mutagenesis program; Nature genetics. 2004. DOI : 10.1038/ng0904-925.
D. Duboule; J. Deschamps : Colinearity loops out; Dev Cell. 2004.
A. Zuniga; O. Michos; F. Spitz; A. P. Haramis; L. Panman et al. : Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression; Genes Dev. 2004. DOI : 10.1101/gad.299904.
J. Zakany; M. Kmita; D. Duboule : A dual role for Hox genes in limb anterior-posterior asymmetry; Science. 2004. DOI : 10.1126/science.1096049.
F. Gachon; P. Fonjallaz; F. Damiola; P. Gos; T. Kodama et al. : The loss of circadian PAR bZip transcription factors results in epilepsy; Genes Dev. 2004. DOI : 10.1101/gad.301404.
D. Duboule : La double histoire de nos doigts; Médecine et Hygiène. 2004.
J. Cobb; D. Duboule : Tracing microRNA patterns in mice; Nat Genet. 2004. DOI : 10.1038/ng1004-1033.

2003

M. Kmita; D. Duboule : Organizing axes in time and space; 25 years of colinear tinkering; Science. 2003.
F. Spitz; F. Gonzalez; D. Duboule : A global control region defines a chromosomal regulatory landscape containing the HoxD cluster; Cell. 2003. DOI : 10.1016/S0092-8674(03)00310-6.
I. Monge; T. Kondo; D. Duboule : An enhancer-titration effect induces digit-specific regulatory alleles of the HoxD cluster; Dev Biol. 2003. DOI : 10.1016/S0012-1606(02)00136-7.
D. Duboule : Time for chronomics?; Science. 2003. DOI : 10.1126/science.301.5631.277.

2002

D. Duboule : Targeted Meiotic Recombination (TAMERE); Wiley Encyclopedia of Molecular Medicine; Wiley Press, 2002. p. 3092-3094.
J.-C. Frachebourg; G. Nivat; D. Duboule : Les nouvelles mutations de l'homme biologique. 2002. XXXVIIIes Rencontre internationales de Genève - Les grandes mutations, Genève, Suisse. p. 46-69.
F. Spitz; T. Montavon; C. Monso-Hinard; M. Morris; M. L. Ventruto et al. : A t(2;8) balanced translocation with breakpoints near the human HOXD complex causes mesomelic dysplasia and vertebral defects; Genomics. 2002. DOI : 10.1006/geno.2002.6735.
N. Preitner; F. Damiola; L. Lopez-Molina; J. Zakany; D. Duboule et al. : The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator; Cell. 2002. DOI : 10.1016/S0092-8674(02)00825-5.
M. Kmita; B. Tarchini; D. Duboule; Y. Herault : Evolutionary conserved sequences are required for the insulation of the vertebrate Hoxd complex in neural cells; Development. 2002. DOI : 10.1242/dev.00151.
M. Kmita; N. Fraudeau; Y. Herault; D. Duboule : Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs; Nature. 2002. DOI : 10.1038/nature01189.
Y. Herault; M. Kmita; C. C. Sawaya; D. Duboule : A nested deletion approach to generate Cre deleter mice with progressive Hox profiles; Int J Dev Biol. 2002.
D. Duboule : Les nouvelles mutations de l'homme biologique; Médecine et Hygiène. 2002.
D. Duboule : Making progress with limb models; Nature. 2002. DOI : 10.1038/418492a.
M. Buscaglia; D. Duboule : Developmental biology in Geneva: a three century-long tradition; Int J Dev Biol. 2002.
P. Ashby; T. Chinnah; J. Zakany; D. Duboule; C. Tickle : 18 Muscle and tendon pattern is altered independently of skeletal pattern in HoxD mutant limbs; J Anat. 2002.

2001

J. Zakany; M. Kmita; P. Alarcon; J. L. de la Pompa; D. Duboule : Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock; Cell. 2001. DOI : 10.1016/S0092-8674(01)00436-6.
F. Spitz; F. Gonzalez; C. Peichel; T. F. Vogt; D. Duboule et al. : Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations; Genes Dev. 2001. DOI : 10.1101/gad.205701.
F. Spitz; D. Duboule : Development. The art of making a joint; Science. 2001. DOI : 10.1126/science.1059665.
L. Michalik; B. Desvergne; N. S. Tan; S. Basu-Modak; P. Escher et al. : Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice; J Cell Biol. 2001. DOI : 10.1083/jcb.200011148.
S. Bruneau; K. R. Johnson; M. Yamamoto; A. Kuroiwa; D. Duboule : The mouse Hoxd13(spdh) mutation, a polyalanine expansion similar to human type II synpolydactyly (SPD), disrupts the function but not the expression of other Hoxd genes; Dev Biol. 2001. DOI : 10.1006/dbio.2001.0382.

2000

Y. Hérault; T. Kondo; J. Zakany; D. Duboule; K.-O. Jacobson et al. : Limb morphogenesis and evolution: The molecular genetics approach. 2000. p. 115-124.
M. Kmita; F. van Der Hoeven; J. Zakany; R. Krumlauf; D. Duboule : Mechanisms of Hox gene colinearity: transposition of the anterior Hoxb1 gene into the posterior HoxD complex; Genes Dev. 2000.
M. Kmita; T. Kondo; D. Duboule : Targeted inversion of a polar silencer within the HoxD complex re-allocates domains of enhancer sharing; Nat Genet. 2000. DOI : 10.1038/82593.
D. Duboule : Developmental genetics. A Hox by any other name; Nature. 2000. DOI : 10.1038/35001179.

1999

J. Zakany; D. Duboule : Hox genes in digit development and evolution; Cell Tissue Res. 1999.
T. F. Vogt; D. Duboule : Antagonists go out on a limb; Cell. 1999.
J. Zakany; D. Duboule : Hox genes and the making of sphincters; Nature. 1999. DOI : 10.1038/44511.
T. Kondo; D. Duboule : Breaking colinearity in the mouse HoxD complex; Cell. 1999. DOI : 10.1016/S0092-8674(00)80749-7.
Y. Herault; J. Beckers; M. Gerard; D. Duboule : Hox gene expression in limbs: colinearity by opposite regulatory controls; Dev Biol. 1999. DOI : 10.1006/dbio.1998.9179.
D. Duboule : No milk today (my Hox have gone away); Proc Natl Acad Sci U.S.A. 1999. DOI : 10.1073/pnas.96.2.322.

1998

D. Duboule; F. van Der Hoeven; Y. Hérault; T. Kondo; J. Zakany : Targeted deficiency in the mouse HoxD complex: compound digit defects as a model for the human synpolydactyly syndrome. 1998. p. 229-235.
T. Kondo; Y. Herault; J. Zakany; D. Duboule : Genetic control of murine limb morphogenesis: relationships with human syndromes and evolutionary relevance; Mol Cell Endocrinol. 1998.
D. Duboule; A. S. Wilkins : The evolution of 'bricolage'; Trends Genet. 1998.
D. Duboule : Vertebrate hox gene regulation: clustering and/or colinearity?; Curr Opin Genet Dev. 1998.
D. Duboule : Hox is in the hair: a break in colinearity?; Genes Dev. 1998.
C. Stoll; D. Duboule; L. B. Holmes; J. Spranger : Classification of limb defects; Am J Med Genet. 1998. DOI : 10.1002/(SICI)1096-8628(19980605)77:5<439::AID-AJMG16>3.0.CO;2-J.
T. Kondo; J. Zakany; D. Duboule : Control of colinearity in AbdB genes of the mouse HoxD complex; Mol Cell. 1998. DOI : 10.1016/S1097-2765(00)80029-5.
Y. Herault; M. Rassoulzadegan; F. Cuzin; D. Duboule : Engineering chromosomes in mice through targeted meiotic recombination (TAMERE); Nat Genet. 1998. DOI : 10.1038/3861.
Y. Hérault; D. Duboule : Comment se construisent nos doigts; La Recherche. 1998.
Y. Herault; J. Beckers; T. Kondo; N. Fraudeau; D. Duboule : Genetic analysis of a Hoxd-12 regulatory element reveals global versus local modes of controls in the HoxD complex; Development. 1998.
J. Beckers; D. Duboule : Genetic analysis of a conserved sequence in the HoxD complex: regulatory redundancy or limitations of the transgenic approach?; Dev Dyn. 1998. DOI : 10.1002/(SICI)1097-0177(199809)213:1<1::AID-AJA1>3.0.CO;2-L.

1997

R. Zeller; D. Duboule : Dorso-ventral limb polarity and origin of the ridge: on the fringe of independence?; Bioessays. 1997.
Y. Herault; T. Kondo; J. Zakany; D. Duboule : Hox genes and genetic control of limb development [Les genes Hox et le controle genetique de la fabrication des membres]; Arch Pediatr. 1997.
Y. Herault; D. Duboule : Control of limb morphogenesis by the Hox genes [Le controle de la morphogenese des membres par les genes Hox]; C R Seances Soc Biol Fil. 1997.
J. Zakany; M. Gerard; B. Favier; D. Duboule : Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum; Embo J. 1997. DOI : 10.1093/emboj/16.14.4393.
J. Zakany; C. Fromental-Ramain; X. Warot; D. Duboule : Regulation of number and size of digits by posterior Hox genes: a dose-dependent mechanism with potential evolutionary implications; Proc Natl Acad Sci U.S.A. 1997. DOI : 10.1073/pnas.94.25.13695.
C. A. Podlasek; D. Duboule; W. Bushman : Male accessory sex organ morphogenesis is altered by loss of function of Hoxd-13; Dev Dyn. 1997. DOI : 10.1002/(SICI)1097-0177(199704)208:4<454::AID-AJA2>3.0.CO;2-H.
T. Kondo; J. Zakany; J. W. Innis; D. Duboule : Of fingers, toes and penises; Nature. 1997. DOI : 10.1038/36234.
Y. Herault; N. Fraudeau; J. Zakany; D. Duboule : Ulnaless (Ul), a regulatory mutation inducing both loss-of-function and gain-of-function of posterior Hoxd genes; Development. 1997.
M. Gerard; J. Zakany; D. Duboule : Interspecies exchange of a Hoxd enhancer in vivo induces premature transcription and anterior shift of the sacrum; Dev Biol. 1997. DOI : 10.1006/dbio.1997.8679.
D. Duboule; P. Sordino : L'origine des doigts; La Recherche. 1997.
D. Duboule : The evolution of genomics; Science. 1997. DOI : 10.1126/science.278.5338.555.

1996

Y. Herault; D. Duboule : Genetic control of limb development [Le controle genetique du developpement des membres]; Ann Genet. 1996.
J. Zakany; M. Gerard; B. Favier; S. S. Potter; D. Duboule : Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning; Dev Biol. 1996. DOI : 10.1006/dbio.1996.0137.
J. Zakany; D. Duboule : Synpolydactyly in mice with a targeted deficiency in the HoxD complex; Nature. 1996. DOI : 10.1038/384069a0.
F. van der Hoeven; J. Zakany; D. Duboule : Gene transpositions in the HoxD complex reveal a hierarchy of regulatory controls; Cell. 1996. DOI : 10.1016/S0092-8674(00)81303-3.
F. van der Hoeven; P. Sordino; N. Fraudeau; J. C. Izpisua-Belmonte; D. Duboule : Teleost HoxD and HoxA genes: comparison with tetrapods and functional evolution of the HOXD complex; Mech Dev. 1996. DOI : 10.1016/0925-4773(95)00455-6.
P. Sordino; D. Duboule; T. Kondo : Zebrafish Hoxa and Evx-2 genes: cloning, developmental expression and implications for the functional evolution of posterior Hox genes; Mech Dev. 1996. DOI : 10.1016/0925-4773(96)00587-4.
P. Sordino; D. Duboule : A molecular approach to the evolution of vertebrate paired appendages; Trends Ecol Evol. 1996. DOI : 10.1016/0169-5347(96)81089-5.
T. Kondo; P. Dolle; J. Zakany; D. Duboule : Function of posterior HoxD genes in the morphogenesis of the anal sphincter; Development. 1996.
Y. Herault; S. Hraba-Renevey; F. van der Hoeven; D. Duboule : Function of the Evx-2 gene in the morphogenesis of vertebrate limbs; Embo J. 1996.
Y. Hérault; D. Duboule : Le contrôle génétique du développement des membres; Ann. génét.. 1996.
M. Gerard; J. Y. Chen; H. Gronemeyer; P. Chambon; D. Duboule et al. : In vivo targeted mutagenesis of a regulatory element required for positioning the Hoxd-11 and Hoxd-10 expression boundaries; Genes Dev. 1996. DOI : 10.1101/gad.10.18.2326.
D. Duboule; P. Sordino : From fins to limbs: Towards a molecular approach to the evolution of vertebrate paired appendages; M S-Med Sci. 1996.
J. Beckers; M. Gerard; D. Duboule : Transgenic analysis of a potential Hoxd-11 limb regulatory element present in tetrapods and fish; Dev Biol. 1996. DOI : 10.1006/dbio.1996.0327.